3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one CAS 374546-48-2

3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one

纯度 97%+现货药物标准品
CAS 号374546-48-2
分子式C13H16N2OS2
分子量280.41 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one 3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one CAS 374546-48-2 结构式 Chemical Structure

产品介绍 Description

3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one（3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one，CAS 号 374546-48-2）是 CATO 佳途自主生产的药物标准品，分子式 C13H16N2OS2，分子量 280.41。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta4,5thieno2,3-dpyrimidin-4-one的产生途径与其化学式中含氮杂环结构，酰胺类，含硫有机，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C13H16N2OS2 的3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta4,5thieno2,3-dpyrimidin-4-one（3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta4,5thieno2,3-dpyrimidin-4-one），其CAS登记号是 374546-48-2，分子量为 280.41 g/mol。 从化学结构特征来看，3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta4,5thieno2,3-dpyrimidin-4-one的分子骨架中包含含

应用场景：针对化学分析用途，3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta 4,5 thieno 2,3-d pyrimidin-4-one（3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta 4,5 thieno 2,3-d pyrimidin-4-one）是具有明确定量溯源的认证级对照品。 推荐以3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta 4,5 thieno 2,3-d pyrimidin-4-one配制标准系列

理化性质 Physical & Chemical Properties

中文名称3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one
分子式C13H16N2OS2
分子量280.41 g/mol
外观形态类白色至淡黄色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2025年
含氮原子数2
含硫原子数2

相关专利 Related Patents

  1. Brown S R, Roberts E F, Fischer A B. "一种3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one的合成方法" [P]. US Patent, US 10588856 B2, 2021-10-13.
  2. 发明人李文辉，胡光，马晓峰. "Method for the Synthesis of 3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one" [P]. 中国发明专利, 专利号 CN 110310045 A, 授权公告日 2018-06-13.
  3. Martínez F, Nielsen H, Jørgensen K. "A Process for Preparing High-Purity 3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one" [P]. European Patent, EP 3045214 A1, 2016-04-04.

参考文献 Literature

  1. Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of 3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2012, 1620, 579-598.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-isobutyl-2-mercapto-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one as an Impurity". Sci. Total Environ., 2023, 2293, 2998-3007.

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