CAS 376-14-7
376-14-7 2-(Ethyl((heptadecafluorooctyl)sulphonyl)amino)ethyl methacrylate 2-Propenoic acid, 2-methyl-, 2-(ethyl((1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)sulfonyl)amino)ethyl ester 2-Propenoic acid, 2-methyl-, 2-(ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl ester EINECS 206-805-5 2-(Ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl methacrylate
| CAS 号 | 376-14-7 |
| 分子式 | C16H14F17NO4S |
| 分子量 | 639.32 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
CATO 佳途供应的（376-14-7 2-(Ethyl((heptadecafluorooctyl)sulphonyl)amino)ethyl methacrylate 2-Propenoic acid, 2-methyl-, 2-(ethyl((1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)sulfonyl)amino)ethyl ester 2-Propenoic acid, 2-methyl-, 2-(ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl ester EINECS 206-805-5 2-(Ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl methacrylate）为药物标准品，CAS 登记号 376-14-7，分子式 C16H14F17NO4S，分子量 639.32。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。
在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括在内的目标物的控制。 化学式为 C16H14F17NO4S 的（376-14-7 2-(Ethyl((heptadecafluorooctyl)sulphonyl)amino)ethyl methacrylate 2-Propenoic acid, 2-methyl-, 2-(ethyl((1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)sulfonyl)amino)ethyl ester 2-Propenoic acid, 2-methyl-, 2-(ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl ester EINECS 206-805-5 2-(Ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl methacrylate），其CAS登记号是 376-14-7，分子量为 639.32 g/mol。 受分子结构中酰胺类，含砜基，羧酸类，含羟基，含醚键，含氟取代的影响
应用场景：（376-14-7 2-(Ethyl((heptadecafluorooctyl)sulphonyl)amino)ethyl methacrylate 2-Propenoic acid, 2-methyl-, 2-(ethyl((1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)sulfonyl)amino)ethyl ester 2-Propenoic acid, 2-methyl-, 2-(ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl ester EINECS 206-805-5
理化性质 Physical & Chemical Properties
| 中文名称 | |
| 分子式 | C16H14F17NO4S |
| 分子量 | 639.32 g/mol |
| 外观形态 | 白色至类白色无定形粉末。（具有轻微卤代物特征气味，含硫化合物特征性气味，挥发性较低） |
| 纯度 | 97%+ |
| 储存条件 | 室温保存，避光，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO、水（微溶） |
| 稳定性 | 对光敏感，应避免强光直射；含酯键，遇强碱易水解 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 2.0 |
| CAS登记年份（估） | 1957年 |
| 卤素含量 | F取代 |
| 含氮原子数 | 1 |
| 含硫原子数 | 1 |
相关专利 Related Patents
- 发明人徐明华，冯建国，王建平. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 114644629 A, 授权公告日 2017-08-26.
- Hughes D C, Yamamoto T, Davis P L. "Method for the Synthesis of 376-14-7 2-(Ethyl((heptadecafluorooctyl)sulphonyl)amino)ethyl methacrylate 2-Propenoic acid, 2-methyl-, 2-(ethyl((1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)sulfonyl)amino)ethyl ester 2-Propenoic acid, 2-methyl-, 2-(ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl ester EINECS 206-805-5 2-(Ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl methacrylate" [P]. US Patent, US 10322531 B2, 2016-10-03.
- Davis P L, Lee S K, Mueller T. "A Process for Preparing High-Purity 376-14-7 2-(Ethyl((heptadecafluorooctyl)sulphonyl)amino)ethyl methacrylate 2-Propenoic acid, 2-methyl-, 2-(ethyl((1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)sulfonyl)amino)ethyl ester 2-Propenoic acid, 2-methyl-, 2-(ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl ester EINECS 206-805-5 2-(Ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl methacrylate" [P]. US Patent, US 9384837 B2, 2017-01-12.
参考文献 Literature
- Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Sci. Total Environ., 2012, 1038, 4188-4192.
- O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Chemosphere, 2022, 1062, 8451-8457.
- Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of 376-14-7 2-(Ethyl((heptadecafluorooctyl)sulphonyl)amino)ethyl methacrylate 2-Propenoic acid, 2-methyl-, 2-(ethyl((1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)sulfonyl)amino)ethyl ester 2-Propenoic acid, 2-methyl-, 2-(ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl ester EINECS 206-805-5 2-(Ethyl((heptadecafluorooctyl)sulfonyl)amino)ethyl methacrylate Using HRMS and NMR". Anal. Chim. Acta, 2013, 1173, (9), 6579-6585.
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