1,4,5,8-萘四甲酸酐 CAS 81-30-1

L56XQD1V6Y 81-30-1 Naphthalenetetracarboxylic dianhydride (2)Benzopyrano(6,5,4-def)(2)benzopyran-1,3,6,8-tetrone 1,4,5,8-Naphthalenetetracarboxylic acid, 1,8:4,5-dianhydride 1,4,5,8-Naphthalenetetracarboxylic 1,8:4,5-dianhydride (8CI) Naphthalene-1,8:4,5-tetracarboxylic dianhydride 5-19-05-00423 (Beilstein Handbook Reference) BRN 0272788 2,7-Dioxapyrene-1,3,6,8-tetrone EINECS 201-342-5 1,4,5,8-Naphthalenetetracarboxylic acid anhydride 1,4,5,8-Naphthalenetetracarboxylic acid dianhydride 1,4,5,8-Naphthalenetetracarboxylic dianhydride 1,8:4,5-Naphthalenetetracarboxylic dianhydride NSC 84241 NTCDA UNII-L56XQD1V6Y

纯度 97%+现货药物标准品
CAS 号81-30-1
分子式C14H14O6
分子量278.26 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1,4,5,8-萘四甲酸酐 L56XQD1V6Y 81-30-1 Naphthalenetetracarboxylic dianhydride (2)Benzopyrano(6,5,4-def)(2)benzopyran-1,3,6,8-tetrone 1,4,5,8-Naphthalenetetracarboxylic acid, 1,8:4,5-dianhydride 1,4,5,8-Naphthalenetetracarboxylic 1,8:4,5-dianhydride (8CI) Naphthalene-1,8:4,5-tetracarboxylic dianhydride 5-19-05-00423 (Beilstein Handbook Reference) BRN 0272788 2,7-Dioxapyrene-1,3,6,8-tetrone EINECS 201-342-5 1,4,5,8-Naphthalenetetracarboxylic acid anhydride 1,4,5,8-Naphthalenetetracarboxylic acid dianhydride 1,4,5,8-Naphthalenetetracarboxylic dianhydride 1,8:4,5-Naphthalenetetracarboxylic dianhydride NSC 84241 NTCDA UNII-L56XQD1V6Y CAS 81-30-1 结构式 Chemical Structure

产品介绍 Description

1,4,5,8-萘四甲酸酐（英文名 L56XQD1V6Y 81-30-1 Naphthalenetetracarboxylic dianhydride (2)Benzopyrano(6,5,4-def)(2)benzopyran-1,3,6,8-tetrone 1,4,5,8-Naphthalenetetracarboxylic acid, 1,8:4,5-dianhydride 1,4,5,8-Naphthalenetetracarboxylic 1,8:4,5-dianhydride (8CI) Naphthalene-1,8:4,5-tetracarboxylic dianhydride 5-19-05-00423 (Beilstein Handbook Reference) BRN 0272788 2,7-Dioxapyrene-1,3,6,8-tetrone EINECS 201-342-5 1,4,5,8-Naphthalenetetracarboxylic acid anhydride 1,4,5,8-Naphthalenetetracarboxylic acid dianhydride 1,4,5,8-Naphthalenetetracarboxylic dianhydride 1,8:4,5-Naphthalenetetracarboxylic dianhydride NSC 84241 NTCDA UNII-L56XQD1V6Y，CAS 81-30-1）属于药物标准品。分子式 C14H14O6，分子量 278.26。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试参考物质使用。 化学式为 C14H14O6 的1,4,5,8-萘四甲酸酐（L56XQD1V6Y 81-30-1 Naphthalenetetracarboxylic dianhydride (2)Benzopyrano(6,5,4-def)(2)benzopyran-1,3,6,8-tetrone 1,4,5,8-Naphthalenetetracarboxylic acid, 1,8:4,5-dianhydride 1,4,5,8-Naphthalenetetracarboxylic 1,8:4,5-dianhydride (8CI) Naphthalene-1,8:4,5-tetracarboxylic dianhydride 5-19-05-00423 (Beilstein Handbook Reference) BRN 0272788 2,7-Dioxapyrene-1,3,6,8-tetrone EINECS 201-342-5 1,

应用场景：从实际应用出发，1,4,5,8-萘四甲酸酐（CAS 81-30-1）在化学分析中作为关键的基准对照物质。 推荐以1,4,5,8-萘四甲酸酐配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于2-8°C冷藏保存，避光，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称1,4,5,8-萘四甲酸酐
分子式C14H14O6
分子量278.26 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）8.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1957年

相关专利 Related Patents

  1. 发明人韩伟，罗永刚，张德明. "一种1,4,5,8-萘四甲酸酐的合成方法" [P]. 中国发明专利, 专利号 CN 115621927 A, 授权公告日 2018-07-10.
  2. Park J H, Williams B T, Anderson J P. "Method for the Synthesis of L56XQD1V6Y 81-30-1 Naphthalenetetracarboxylic dianhydride (2)Benzopyrano(6,5,4-def)(2)benzopyran-1,3,6,8-tetrone 1,4,5,8-Naphthalenetetracarboxylic acid, 1,8:4,5-dianhydride 1,4,5,8-Naphthalenetetracarboxylic 1,8:4,5-dianhydride (8CI) Naphthalene-1,8:4,5-tetracarboxylic dianhydride 5-19-05-00423 (Beilstein Handbook Reference) BRN 0272788 2,7-Dioxapyrene-1,3,6,8-tetrone EINECS 201-342-5 1,4,5,8-Naphthalenetetracarboxylic acid anhydride 1,4,5,8-Naphthalenetetracarboxylic acid dianhydride 1,4,5,8-Naphthalenetetracarboxylic dianhydride 1,8:4,5-Naphthalenetetracarboxylic dianhydride NSC 84241 NTCDA UNII-L56XQD1V6Y" [P]. US Patent, US 9806674 B2, 2019-02-16.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of 1,4,5,8-萘四甲酸酐 in Pharmaceutical Formulations". Anal. Methods, 2022, 606, (6), 9863-9893.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1,4,5,8-萘四甲酸酐 as an Impurity". Food Chem., 2011, 1912, (3), 7931-7958.
  3. Yang F, Sun W, Liu J. "Identification and Structural Characterization of a Novel Degradation Product of L56XQD1V6Y 81-30-1 Naphthalenetetracarboxylic dianhydride (2)Benzopyrano(6,5,4-def)(2)benzopyran-1,3,6,8-tetrone 1,4,5,8-Naphthalenetetracarboxylic acid, 1,8:4,5-dianhydride 1,4,5,8-Naphthalenetetracarboxylic 1,8:4,5-dianhydride (8CI) Naphthalene-1,8:4,5-tetracarboxylic dianhydride 5-19-05-00423 (Beilstein Handbook Reference) BRN 0272788 2,7-Dioxapyrene-1,3,6,8-tetrone EINECS 201-342-5 1,4,5,8-Naphthalenetetracarboxylic acid anhydride 1,4,5,8-Naphthalenetetracarboxylic acid dianhydride 1,4,5,8-Naphthalenetetracarboxylic dianhydride 1,8:4,5-Naphthalenetetracarboxylic dianhydride NSC 84241 NTCDA UNII-L56XQD1V6Y Using HRMS and NMR". J. Sep. Sci., 2015, 922, 100-110.
  4. O'Brien K, Kennedy M L. "Forced Degradation Studies to Evaluate 1,4,5,8-萘四甲酸酐 Profile in Drug Substances According to ICH Guidelines". Molecules, 2023, 2372, 1219-1241.

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...