CAS 813452-18-5

9Z723VGH7J 813452-18-5 Carmegliptin [USAN:INN] 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J

纯度 97%+现货药物标准品
CAS 号813452-18-5
分子式C20H28FN3O3
分子量377.45 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

9Z723VGH7J 813452-18-5 Carmegliptin [USAN:INN] 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J CAS 813452-18-5 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的（9Z723VGH7J 813452-18-5 Carmegliptin [USAN:INN] 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J）为药物标准品，CAS 登记号 813452-18-5，分子式 C20H28FN3O3，分子量 377.45。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

与同类药物标准品相比，的分子量为377.45 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C20H28FN3O3 的（9Z723VGH7J 813452-18-5 Carmegliptin USAN:INN 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J），其CAS登记号是 813452-18-5，分子量为 377.45 g/mol。 依据分子式为 C20H28FN3O3 的

应用场景：（9Z723VGH7J 813452-18-5 Carmegliptin USAN:INN 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)p

理化性质 Physical & Chemical Properties

中文名称
分子式C20H28FN3O3
分子量377.45 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）8.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1986年
卤素含量F取代
含氮原子数3

相关专利 Related Patents

  1. 发明人陈志强，冯建国，黄志刚. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 110534678 B, 授权公告日 2024-05-10.
  2. 发明人何建平，冯建国，朱建伟. "Method for the Synthesis of 9Z723VGH7J 813452-18-5 Carmegliptin [USAN:INN] 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J" [P]. 中国发明专利, 专利号 CN 117780688 A, 授权公告日 2022-02-15.
  3. 发明人朱建伟，李文辉，刘建华. "A Process for Preparing High-Purity 9Z723VGH7J 813452-18-5 Carmegliptin [USAN:INN] 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J" [P]. 中国发明专利, 专利号 CN 117816094 A, 授权公告日 2023-06-07.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". J. Nat. Prod., 2010, 1965, 6753-6770.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Talanta, 2024, 861, 2728-2738.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of 9Z723VGH7J 813452-18-5 Carmegliptin [USAN:INN] 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J Using HRMS and NMR". Molecules, 2012, 1181, 1791-1815.

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...