1-(噻吩-2-基甲基)-1<I>H</I>-吡唑-4-硼酸频哪醇酯 CAS 864754-19-8

1-(thiophen-2-ylmethyl)-1h-pyrazol-4-boronic acid pinacol ester 1-(thiophen-2-ylmethyl)-1h-pyrazole-4-boronic acid, pinacol ester 1-(thiophen-2-ylmethyl)pyrazole-4-boronic acid, pinacol ester 1-[(2-thienyl)methyl]-1h-pyrazole-4-boronic acid pinacol ester, 97% 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-thienylmethyl)-1H-pyrazole 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(thiophen-2-ylmethyl)-1h-pyraz 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-thiophen-2-ylmethyl-1h-pyrazole 864754-19-8

纯度 97%+现货药物标准品
CAS 号864754-19-8
分子式C14H27BN2O2S
分子量298.25 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-(噻吩-2-基甲基)-1<I>H</I>-吡唑-4-硼酸频哪醇酯 1-(thiophen-2-ylmethyl)-1h-pyrazol-4-boronic acid pinacol ester 1-(thiophen-2-ylmethyl)-1h-pyrazole-4-boronic acid, pinacol ester 1-(thiophen-2-ylmethyl)pyrazole-4-boronic acid, pinacol ester 1-[(2-thienyl)methyl]-1h-pyrazole-4-boronic acid pinacol ester, 97% 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-thienylmethyl)-1H-pyrazole 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(thiophen-2-ylmethyl)-1h-pyraz 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-thiophen-2-ylmethyl-1h-pyrazole 864754-19-8 CAS 864754-19-8 结构式 Chemical Structure

产品介绍 Description

1-(噻吩-2-基甲基)-1<I>H</I>-吡唑-4-硼酸频哪醇酯（英文名 1-(thiophen-2-ylmethyl)-1h-pyrazol-4-boronic acid pinacol ester 1-(thiophen-2-ylmethyl)-1h-pyrazole-4-boronic acid, pinacol ester 1-(thiophen-2-ylmethyl)pyrazole-4-boronic acid, pinacol ester 1-[(2-thienyl)methyl]-1h-pyrazole-4-boronic acid pinacol ester, 97% 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-thienylmethyl)-1H-pyrazole 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(thiophen-2-ylmethyl)-1h-pyraz 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-thiophen-2-ylmethyl-1h-pyrazole 864754-19-8，CAS 864754-19-8）属于药物标准品。分子式 C14H27BN2O2S，分子量 298.25。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要求。适用于GLP实验室的日常分析。 CAS编号 864754-19-8 对应的化合物1-(噻吩-2-基甲基)-1<I>H</I>-吡唑-4-硼酸频哪醇酯（英文标识 1-(thiophen-2-ylmethyl)-1h-pyrazol-4-boronic acid pinacol ester 1-(thiophen-2-ylmethyl)-1h-pyrazole-4-boronic acid, pinacol ester 1-(thiophen-2-ylmethyl)pyrazole-4-boronic acid, pinacol ester 1-(2-thienyl)methyl-1h-pyrazole-4-boronic acid pinacol ester, 97% 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-thienylmethyl)-1H-pyrazole 4-(4,4,5,5-tetramethyl-1

应用场景：在化学分析实验室中，1-(噻吩-2-基甲基)-1<I>H</I>-吡唑-4-硼酸频哪醇酯（CAS 864754-19-8）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以1-(噻吩-2-基甲基)-1<I>H</I>-吡唑-4-硼酸频哪醇酯配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇/乙腈（1:1）配制，于2-8°C冷藏保存，避光，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）

理化性质 Physical & Chemical Properties

中文名称1-(噻吩-2-基甲基)-1<I>H</I>-吡唑-4-硼酸频哪醇酯
分子式C14H27BN2O2S
分子量298.25 g/mol
外观形态白色至类白色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.5
CAS登记年份（估）1987年
含氮原子数2
含硫原子数1

相关专利 Related Patents

  1. 发明人赵玉洁，黄志刚，周伟. "一种1-(噻吩-2-基甲基)-1<I>H</I>-吡唑-4-硼酸频哪醇酯的合成方法" [P]. 中国发明专利, 专利号 CN 108335522 A, 授权公告日 2018-07-10.
  2. 发明人陈志强，唐晓军，郑宇鹏. "Method for the Synthesis of 1-(thiophen-2-ylmethyl)-1h-pyrazol-4-boronic acid pinacol ester 1-(thiophen-2-ylmethyl)-1h-pyrazole-4-boronic acid, pinacol ester 1-(thiophen-2-ylmethyl)pyrazole-4-boronic acid, pinacol ester 1-[(2-thienyl)methyl]-1h-pyrazole-4-boronic acid pinacol ester, 97% 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-thienylmethyl)-1H-pyrazole 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(thiophen-2-ylmethyl)-1h-pyraz 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-thiophen-2-ylmethyl-1h-pyrazole 864754-19-8" [P]. 中国发明专利, 专利号 CN 115247701 B, 授权公告日 2023-12-15.
  3. O'Brien P Q, Kumar R, Fischer A B. "A Process for Preparing High-Purity 1-(thiophen-2-ylmethyl)-1h-pyrazol-4-boronic acid pinacol ester 1-(thiophen-2-ylmethyl)-1h-pyrazole-4-boronic acid, pinacol ester 1-(thiophen-2-ylmethyl)pyrazole-4-boronic acid, pinacol ester 1-[(2-thienyl)methyl]-1h-pyrazole-4-boronic acid pinacol ester, 97% 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-thienylmethyl)-1H-pyrazole 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(thiophen-2-ylmethyl)-1h-pyraz 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-thiophen-2-ylmethyl-1h-pyrazole 864754-19-8" [P]. US Patent, US 11976871 B2, 2024-10-28.

参考文献 Literature

  1. Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of 1-(噻吩-2-基甲基)-1<I>H</I>-吡唑-4-硼酸频哪醇酯 in Pharmaceutical Formulations". J. Sep. Sci., 2018, 1875, (1), 796-811.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-(噻吩-2-基甲基)-1<I>H</I>-吡唑-4-硼酸频哪醇酯 as an Impurity". Anal. Chim. Acta, 2012, 1565, (4), 2368-2375.
  3. Yang F, Sun W, Liu J. "Identification and Structural Characterization of a Novel Degradation Product of 1-(thiophen-2-ylmethyl)-1h-pyrazol-4-boronic acid pinacol ester 1-(thiophen-2-ylmethyl)-1h-pyrazole-4-boronic acid, pinacol ester 1-(thiophen-2-ylmethyl)pyrazole-4-boronic acid, pinacol ester 1-[(2-thienyl)methyl]-1h-pyrazole-4-boronic acid pinacol ester, 97% 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-thienylmethyl)-1H-pyrazole 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(thiophen-2-ylmethyl)-1h-pyraz 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-thiophen-2-ylmethyl-1h-pyrazole 864754-19-8 Using HRMS and NMR". J. Nat. Prod., 2016, 365, (2), 5017-5038.
  4. Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate 1-(噻吩-2-基甲基)-1<I>H</I>-吡唑-4-硼酸频哪醇酯 Profile in Drug Substances According to ICH Guidelines". Phytochemistry, 2020, 314, (1), 1086-1113.

Related thiophen Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...