2,4,7,9-四甲基-5-癸炔-4,7-二醇乙氧基化物 CAS 9014-85-1

9014-85-1 Polyethylene glycol 2,4,7,9-tetramethyl-5-decyne-4,7-diyl diether Ethoxylated-2,4,7,9-tetramethyl-5-decyne-4,7-diol Poly(oxy-1,2-ethanediyl), alpha,alpha'-(1,4-dimethyl-1,4-bis(2-methylpropyl)-2-butyne-1,4-diyl)bis(omega-hydroxy- Polyoxyethylene glycol ether with 1,4-diisobutyl-1,4-dimethylbutynediol (2:1) 2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated EC 500-022-5

纯度 97%+现货药物标准品
CAS 号9014-85-1
分子式C14H26O2 C2H6O2
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2,4,7,9-四甲基-5-癸炔-4,7-二醇乙氧基化物 9014-85-1 Polyethylene glycol 2,4,7,9-tetramethyl-5-decyne-4,7-diyl diether Ethoxylated-2,4,7,9-tetramethyl-5-decyne-4,7-diol Poly(oxy-1,2-ethanediyl), alpha,alpha'-(1,4-dimethyl-1,4-bis(2-methylpropyl)-2-butyne-1,4-diyl)bis(omega-hydroxy- Polyoxyethylene glycol ether with 1,4-diisobutyl-1,4-dimethylbutynediol (2:1) 2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated EC 500-022-5 CAS 9014-85-1 结构式 Chemical Structure

产品介绍 Description

2,4,7,9-四甲基-5-癸炔-4,7-二醇乙氧基化物（9014-85-1 Polyethylene glycol 2,4,7,9-tetramethyl-5-decyne-4,7-diyl diether Ethoxylated-2,4,7,9-tetramethyl-5-decyne-4,7-diol Poly(oxy-1,2-ethanediyl), alpha,alpha'-(1,4-dimethyl-1,4-bis(2-methylpropyl)-2-butyne-1,4-diyl)bis(omega-hydroxy- Polyoxyethylene glycol ether with 1,4-diisobutyl-1,4-dimethylbutynediol (2:1) 2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated EC 500-022-5，CAS 号 9014-85-1）是 CATO 佳途自主生产的药物标准品，分子式 C14H26O2 C2H6O2。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

与同类药物标准品相比，2,4,7,9-四甲基-5-癸炔-4,7-二醇乙氧基化物的分子量为288.43 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 9014-85-1 对应的化合物2,4,7,9-四甲基-5-癸炔-4,7-二醇乙氧基化物（英文标识 9014-85-1 Polyethylene glycol 2,4,7,9-tetramethyl-5-decyne-4,7-diyl diether Ethoxylated-2,4,7,9-tetramethyl-5-decyne-4,7-diol Poly(oxy-1,2-ethanediyl), alpha,alpha'-(1,4-dimethyl-1,4-bis(2-methylpropyl)-2-butyne-1,4-diyl)bis(omega-hydroxy- Polyoxyethylene glycol ether with 1,4-diisobutyl-1,4-dimethylbutynediol (2:1) 2,4,7,9-Tetramethyldec-5-yne-4,7-diol,

应用场景：从实际应用出发，2,4,7,9-四甲基-5-癸炔-4,7-二醇乙氧基化物（CAS 9014-85-1）在化学分析中作为关键的基准对照物质。 推荐以2,4,7,9-四甲基-5-癸炔-4,7-二醇乙氧基化物配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于室温保存，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确

理化性质 Physical & Chemical Properties

中文名称2,4,7,9-四甲基-5-癸炔-4,7-二醇乙氧基化物
分子式C14H26O2 C2H6O2
分子量288.43 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1959年

相关专利 Related Patents

  1. Chen K W, Yamamoto T, Klinger H. "一种2,4,7,9-四甲基-5-癸炔-4,7-二醇乙氧基化物的合成方法" [P]. US Patent, US 11203372 B2, 2020-05-12.
  2. 发明人郭海燕，唐晓军，张德明. "Method for the Synthesis of 9014-85-1 Polyethylene glycol 2,4,7,9-tetramethyl-5-decyne-4,7-diyl diether Ethoxylated-2,4,7,9-tetramethyl-5-decyne-4,7-diol Poly(oxy-1,2-ethanediyl), alpha,alpha'-(1,4-dimethyl-1,4-bis(2-methylpropyl)-2-butyne-1,4-diyl)bis(omega-hydroxy- Polyoxyethylene glycol ether with 1,4-diisobutyl-1,4-dimethylbutynediol (2:1) 2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated EC 500-022-5" [P]. 中国发明专利, 专利号 CN 111248773 A, 授权公告日 2015-05-09.
  3. Lefèvre J P, Kowalski A, Johansson L. "A Process for Preparing High-Purity 9014-85-1 Polyethylene glycol 2,4,7,9-tetramethyl-5-decyne-4,7-diyl diether Ethoxylated-2,4,7,9-tetramethyl-5-decyne-4,7-diol Poly(oxy-1,2-ethanediyl), alpha,alpha'-(1,4-dimethyl-1,4-bis(2-methylpropyl)-2-butyne-1,4-diyl)bis(omega-hydroxy- Polyoxyethylene glycol ether with 1,4-diisobutyl-1,4-dimethylbutynediol (2:1) 2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated EC 500-022-5" [P]. European Patent, EP 3241314 A1, 2023-06-23.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of 2,4,7,9-四甲基-5-癸炔-4,7-二醇乙氧基化物 in Pharmaceutical Formulations". Anal. Chem., 2018, 885, 1005-1026.
  2. Smith J A, Johnson M B. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2,4,7,9-四甲基-5-癸炔-4,7-二醇乙氧基化物 as an Impurity". J. Agric. Food Chem., 2019, 2107, (4), 6687-6709.

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