(<I>S</I>)-1-(4-氯苯基)乙醇 CAS 99528-42-4

(S)-1-(4-Chlorophenyl)ethanol (s)-(-)-1-(4-chlorophenyl)-1-ethanol (s)-1-(4-chlorophenyl)ethanol ,97% (s)-1-(4-chlorophenyl)ethanol, (s)-4|I-chloro-1-phenylethanol (s)-4-chloro-1-phenylethanol (s)-4-chloro-alpha-methylbenzyl alcohol (s)-4-chloro-alpha-methylbenzyl alcohol 95% (s)-4-chloro-|A-methylbenzyl alcohol 99528-42-4

纯度 97%+现货药物标准品
CAS 号99528-42-4
分子式C8H15ClO
分子量162.66 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(<I>S</I>)-1-(4-氯苯基)乙醇 (S)-1-(4-Chlorophenyl)ethanol (s)-(-)-1-(4-chlorophenyl)-1-ethanol (s)-1-(4-chlorophenyl)ethanol ,97% (s)-1-(4-chlorophenyl)ethanol, (s)-4|I-chloro-1-phenylethanol (s)-4-chloro-1-phenylethanol (s)-4-chloro-alpha-methylbenzyl alcohol (s)-4-chloro-alpha-methylbenzyl alcohol 95% (s)-4-chloro-|A-methylbenzyl alcohol 99528-42-4 CAS 99528-42-4 结构式 Chemical Structure

产品介绍 Description

(<I>S</I>)-1-(4-氯苯基)乙醇（(S)-1-(4-Chlorophenyl)ethanol (s)-(-)-1-(4-chlorophenyl)-1-ethanol (s)-1-(4-chlorophenyl)ethanol ,97% (s)-1-(4-chlorophenyl)ethanol, (s)-4|I-chloro-1-phenylethanol (s)-4-chloro-1-phenylethanol (s)-4-chloro-alpha-methylbenzyl alcohol (s)-4-chloro-alpha-methylbenzyl alcohol 95% (s)-4-chloro-|A-methylbenzyl alcohol 99528-42-4，CAS 号 99528-42-4）是 CATO 佳途自主生产的药物标准品，分子式 C8H15ClO，分子量 162.66。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

(<I>S</I>)-1-(4-氯苯基)乙醇（(S)-1-(4-Chlorophenyl)ethanol (s)-(-)-1-(4-chlorophenyl)-1-ethanol (s)-1-(4-chlorophenyl)ethanol ,97% (s)-1-(4-chlorophenyl)ethanol, (s)-4|I-chloro-1-phenylethanol (s)-4-chloro-1-phenylethanol (s)-4-chloro-alpha-methylbenzyl alcohol (s)-4-chloro-alpha-methylbenzyl alcohol 95% (s)-4-chloro-|A-methylbenzyl alcohol 99528-42-4），CAS注册编号 99528-42-4，化学分子式为 C8H15ClO，分子量 162.66 g/mol。 (<I>S</I>)-1-(4-氯苯基)乙醇（C8H15ClO）含有含羟基，含醚键，含氯取代。卤素取代增加了化合物的密度和沸点，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。卤素

应用场景：在化学分析实验室中，(<I>S</I>)-1-(4-氯苯基)乙醇（CAS 99528-42-4）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以(<I>S</I>)-1-(4-氯苯基)乙醇配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于2-8°C冷藏保存，密闭保存防止挥发条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用

理化性质 Physical & Chemical Properties

中文名称(<I>S</I>)-1-(4-氯苯基)乙醇
分子式C8H15ClO
分子量162.66 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1985年
卤素含量Cl取代

相关专利 Related Patents

  1. 发明人韩伟，罗永刚，郑宇鹏. "一种(<I>S</I>)-1-(4-氯苯基)乙醇的合成方法" [P]. 中国发明专利, 专利号 CN 112881376 A, 授权公告日 2015-10-14.
  2. Roberts E F, Patel M V, Stevens L M. "Method for the Synthesis of (S)-1-(4-Chlorophenyl)ethanol (s)-(-)-1-(4-chlorophenyl)-1-ethanol (s)-1-(4-chlorophenyl)ethanol ,97% (s)-1-(4-chlorophenyl)ethanol, (s)-4|I-chloro-1-phenylethanol (s)-4-chloro-1-phenylethanol (s)-4-chloro-alpha-methylbenzyl alcohol (s)-4-chloro-alpha-methylbenzyl alcohol 95% (s)-4-chloro-|A-methylbenzyl alcohol 99528-42-4" [P]. US Patent, US 10017011 B2, 2022-09-03.
  3. Hughes D C, Thompson G K, Brown S R. "A Process for Preparing High-Purity (S)-1-(4-Chlorophenyl)ethanol (s)-(-)-1-(4-chlorophenyl)-1-ethanol (s)-1-(4-chlorophenyl)ethanol ,97% (s)-1-(4-chlorophenyl)ethanol, (s)-4|I-chloro-1-phenylethanol (s)-4-chloro-1-phenylethanol (s)-4-chloro-alpha-methylbenzyl alcohol (s)-4-chloro-alpha-methylbenzyl alcohol 95% (s)-4-chloro-|A-methylbenzyl alcohol 99528-42-4" [P]. US Patent, US 11274092 B2, 2019-03-03.

参考文献 Literature

  1. Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of (<I>S</I>)-1-(4-氯苯基)乙醇 in Pharmaceutical Formulations". Anal. Methods, 2016, 164, (2), 8542-8569.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of (<I>S</I>)-1-(4-氯苯基)乙醇 as an Impurity". Talanta, 2025, 1899, (12), 6557-6570.

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