2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro[Indene-1,4'-Piperidine]-3-Yl)Acetic Acid CAS 1160247-57-3

2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro[Indene-1,4'-Piperidine]-3-Yl)Acetic Acid

纯度 97%+现货药物标准品
CAS 号1160247-57-3
分子式C21H29NO4
分子量359.46 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro[Indene-1,4'-Piperidine]-3-Yl)Acetic Acid 2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro[Indene-1,4'-Piperidine]-3-Yl)Acetic Acid CAS 1160247-57-3 结构式 Chemical Structure

产品介绍 Description

CAS 1160247-57-3 对应的2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro[Indene-1,4'-Piperidine]-3-Yl)Acetic Acid（2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro[Indene-1,4'-Piperidine]-3-Yl)Acetic Acid）为 CATO 佳途药物标准品产品线成员。分子式 C21H29NO4，分子量 359.46。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-DihydrospiroIndene-1,4'-Piperidine-3-Yl)Acetic Acid的产生途径与其化学式中黄酮骨架，酰胺类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C21H29NO4 的2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-DihydrospiroIndene-1,4'-Piperidine-3-Yl)Acetic Acid（2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-DihydrospiroIndene-1,4'-Piperidine-3-Yl)Acetic Acid），其CAS登记号是 1160247-57-3，分子量为 359.46 g/mol。 2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-DihydrospiroIndene-1,4'-Piperidine-3-Yl)Acetic Aci

应用场景：2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro Indene-1,4'-Piperidine -3-Yl)Acetic Acid（2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro Indene-1,4'-Piperidine -3-Yl)Acetic Acid）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro Indene-1,4'-Piperidine -3

理化性质 Physical & Chemical Properties

中文名称2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro[Indene-1,4'-Piperidine]-3-Yl)Acetic Acid
分子式C21H29NO4
分子量359.46 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）8.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1989年
含氮原子数1

相关专利 Related Patents

  1. 发明人杨光，刘建华，韩伟. "一种2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro[Indene-1,4'-Piperidine]-3-Yl)Acetic Acid的合成方法" [P]. 中国发明专利, 专利号 CN 108942335 B, 授权公告日 2022-05-26.
  2. Mueller T, Yamamoto T, O'Brien P Q. "Method for the Synthesis of 2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro[Indene-1,4'-Piperidine]-3-Yl)Acetic Acid" [P]. US Patent, US 9517113 B2, 2020-02-15.

参考文献 Literature

  1. Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of 2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro[Indene-1,4'-Piperidine]-3-Yl)Acetic Acid in Pharmaceutical Formulations". J. Agric. Food Chem., 2025, 486, 4946-4970.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-(1'-(Tert-Butoxycarbonyl)-5-Methyl-2,3-Dihydrospiro[Indene-1,4'-Piperidine]-3-Yl)Acetic Acid as an Impurity". Anal. Chem., 2025, 1312, (7), 797-812.

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