(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride CAS 1208724-35-9

(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride

纯度 97%+现货药物标准品
CAS 号1208724-35-9
分子式C12H17NO2 HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride (5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride CAS 1208724-35-9 结构式 Chemical Structure

产品介绍 Description

CAS 1208724-35-9 对应的(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride（(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride）为 CATO 佳途药物标准品产品线成员。分子式 C12H17NO2 HCl。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride的产生途径与其化学式中含氮杂环结构，酰胺类，含羟基，含醚键，含氯取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C12H17NO2 HCl 的(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride（(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride），其CAS登记号是 1208724-35-9，分子量为 243.73 g/mol。 受分子结构中含氮杂环结构，酰胺类，含羟基，含醚键，含氯取代的影响，(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride表现为类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味）。其固体形态

应用场景：在化学分析实验室中，(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride（CAS 1208724-35-9）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器

理化性质 Physical & Chemical Properties

中文名称(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride
分子式C12H17NO2 HCl
分子量243.73 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1990年
卤素含量Cl取代
含氮原子数1

相关专利 Related Patents

  1. 发明人周伟，胡光，陈志强. "一种(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 111332453 A, 授权公告日 2021-08-04.
  2. Rossi M, Nielsen H, Mueller T C. "Method for the Synthesis of (5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride" [P]. European Patent, EP 3131914 A1, 2020-12-23.
  3. Brown S R, Mueller T, Williams B T. "A Process for Preparing High-Purity (5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride" [P]. US Patent, US 9866718 B2, 2020-08-27.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of (5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride in Pharmaceutical Formulations". Molecules, 2012, 1594, (12), 5539-5552.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of (5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride as an Impurity". Anal. Chim. Acta, 2014, 1974, (5), 5890-5909.
  3. Zhang Y, Li Q, Chen T. "Identification and Structural Characterization of a Novel Degradation Product of (5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride Using HRMS and NMR". Environ. Sci. Technol., 2023, 2251, (8), 7456-7480.
  4. Wang L, Li J, Zhang H. "Forced Degradation Studies to Evaluate (5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)methanamine hydrochloride Profile in Drug Substances According to ICH Guidelines". Food Chem., 2022, 139, (4), 4981-5005.

Related ethoxy Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...