CAS 1219707-39-7

1219707-39-7 43EP6XV33E LCB01-0371 UNII-43EP6XV33E (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one 2-Oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)- LCB-010371 LCB-01-0371

纯度 97%+现货药物标准品
CAS 号1219707-39-7
分子式C14H17FN4O3
分子量308.31 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1219707-39-7 43EP6XV33E LCB01-0371 UNII-43EP6XV33E (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one 2-Oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)- LCB-010371 LCB-01-0371 CAS 1219707-39-7 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品（1219707-39-7 43EP6XV33E LCB01-0371 UNII-43EP6XV33E (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one 2-Oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)- LCB-010371 LCB-01-0371，CAS 1219707-39-7），分子式 C14H17FN4O3，分子量 308.31。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

（1219707-39-7 43EP6XV33E LCB01-0371 UNII-43EP6XV33E (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one 2-Oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)- LCB-010371 LCB-01-0371），CAS注册编号 1219707-39-7，化学分子式为 C14H17FN4O3，分子量 308.31 g/mol。 （分子式 C14H17FN4O3）的化学结构中包含含氮杂环结构，酰胺类，含羟基，含醚

应用场景：（1219707-39-7 43EP6XV33E LCB01-0371 UNII-43EP6XV33E (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one 2-Oxazolidinone, 3-(4-(5,6-dihydro-

理化性质 Physical & Chemical Properties

中文名称
分子式C14H17FN4O3
分子量308.31 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）8.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1990年
卤素含量F取代
含氮原子数4

相关专利 Related Patents

  1. 发明人刘建华，何建平，张德明. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 108761571 B, 授权公告日 2023-12-16.
  2. 发明人王建平，陈志强，高志强. "Method for the Synthesis of 1219707-39-7 43EP6XV33E LCB01-0371 UNII-43EP6XV33E (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one 2-Oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)- LCB-010371 LCB-01-0371" [P]. 中国发明专利, 专利号 CN 113432543 B, 授权公告日 2024-02-24.
  3. 发明人周伟，郑宇鹏，胡光. "A Process for Preparing High-Purity 1219707-39-7 43EP6XV33E LCB01-0371 UNII-43EP6XV33E (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one 2-Oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)- LCB-010371 LCB-01-0371" [P]. 中国发明专利, 专利号 CN 111498001 A, 授权公告日 2015-09-02.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2021, 508, 91-119.
  2. Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Chim. Acta, 2024, 247, 3454-3457.
  3. Smith J A, Johnson M B. "Identification and Structural Characterization of a Novel Degradation Product of 1219707-39-7 43EP6XV33E LCB01-0371 UNII-43EP6XV33E (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one 2-Oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)- LCB-010371 LCB-01-0371 Using HRMS and NMR". J. Chromatogr. A, 2010, 1509, 7612-7615.

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