CAS 182250-66-4

182250-66-4 Fmoc-Lys(Adpoc)-OH N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[(1-methyl-1-adamantylethoxy)carbonyl]-L-lysine fmoc-lysine(adpoc)-oh fmoc-ne(1-[1'-adamantyl]-1-methyl-ethoxycarbonyl)-l-lysine n-alpha-(9-fluorenylmethoxycarbonyl)-n-epsilon-[1-(1'-adamantyl)-1-methyl-ethoxycarbonyl]-l-lysine

纯度 97%+现货药物标准品
CAS 号182250-66-4
分子式C35H44N2O6
分子量588.73 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

182250-66-4 Fmoc-Lys(Adpoc)-OH N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[(1-methyl-1-adamantylethoxy)carbonyl]-L-lysine fmoc-lysine(adpoc)-oh fmoc-ne(1-[1'-adamantyl]-1-methyl-ethoxycarbonyl)-l-lysine n-alpha-(9-fluorenylmethoxycarbonyl)-n-epsilon-[1-(1'-adamantyl)-1-methyl-ethoxycarbonyl]-l-lysine CAS 182250-66-4 结构式 Chemical Structure

产品介绍 Description

CAS 182250-66-4 对应的（182250-66-4 Fmoc-Lys(Adpoc)-OH N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[(1-methyl-1-adamantylethoxy)carbonyl]-L-lysine fmoc-lysine(adpoc)-oh fmoc-ne(1-[1'-adamantyl]-1-methyl-ethoxycarbonyl)-l-lysine n-alpha-(9-fluorenylmethoxycarbonyl)-n-epsilon-[1-(1'-adamantyl)-1-methyl-ethoxycarbonyl]-l-lysine）为 CATO 佳途药物标准品产品线成员。分子式 C35H44N2O6，分子量 588.73。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

依据分子式为 C35H44N2O6 的结构特征，其分子内含含氮杂环结构，酰胺类，含羟基，含醚键，这意味着该化合物在紫外光谱中会呈现特征性的吸收带。分子量 588.73 g/mol 这一参数对质谱检测中的分子离子峰识别具有直接参考价值。由于结构中存在共轭发色团，该化合物在200-400 nm区间具有显著的紫外吸收，便于HPLC-UV检测。 化学式为 C35H44N2O6 的（182250-66-4 Fmoc-Lys(Adpoc)-OH N2-(9H-Fluoren-9-ylmethoxy)carbonyl-N6-(1-methyl-1-adamantylethoxy)carbonyl-L-lysine fmoc-lysine(adpoc)-oh fmoc-ne(1-1'-adamantyl-1-methyl-ethoxycarbonyl)-l-lysine n-alpha-(9-fluorenylmethoxycarbonyl)-n-epsilon-1-(1'-adamantyl)-1-methyl-ethoxycarbonyl-l-lysine），其CAS登记号是 1

应用场景：（182250-66-4 Fmoc-Lys(Adpoc)-OH N2- (9H-Fluoren-9-ylmethoxy)carbonyl -N6- (1-methyl-1-adamantylethoxy)carbonyl -L-lysine fmoc-lysine(adpoc)-oh fmoc-ne(1- 1'-adamantyl -1-methyl-ethoxycarbonyl)-l-lysine n-alpha-(9-fluorenylmethoxycarbonyl)-n-epsilon- 1-(1'-adamantyl)-1-methyl-ethoxycarbonyl -l-lysine

理化性质 Physical & Chemical Properties

中文名称
分子式C35H44N2O6
分子量588.73 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）15.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2009年
含氮原子数2

相关专利 Related Patents

  1. 发明人孙丽萍，王建平，张德明. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 114301173 B, 授权公告日 2019-01-24.
  2. Schröder R, Lee S K, Thompson G K. "Method for the Synthesis of 182250-66-4 Fmoc-Lys(Adpoc)-OH N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[(1-methyl-1-adamantylethoxy)carbonyl]-L-lysine fmoc-lysine(adpoc)-oh fmoc-ne(1-[1'-adamantyl]-1-methyl-ethoxycarbonyl)-l-lysine n-alpha-(9-fluorenylmethoxycarbonyl)-n-epsilon-[1-(1'-adamantyl)-1-methyl-ethoxycarbonyl]-l-lysine" [P]. US Patent, US 9403896 B2, 2024-03-04.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Phytochemistry, 2016, 781, (11), 1962-1985.
  2. Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Food Chem., 2023, 1817, 8536-8553.
  3. Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of 182250-66-4 Fmoc-Lys(Adpoc)-OH N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[(1-methyl-1-adamantylethoxy)carbonyl]-L-lysine fmoc-lysine(adpoc)-oh fmoc-ne(1-[1'-adamantyl]-1-methyl-ethoxycarbonyl)-l-lysine n-alpha-(9-fluorenylmethoxycarbonyl)-n-epsilon-[1-(1'-adamantyl)-1-methyl-ethoxycarbonyl]-l-lysine Using HRMS and NMR". Anal. Methods, 2016, 925, (5), 9832-9862.
  4. Brown R C, Davis S M. "Forced Degradation Studies to Evaluate Profile in Drug Substances According to ICH Guidelines". J. Pharm. Biomed. Anal., 2019, 923, (10), 8601-8621.

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