3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2-yl]-2,6-piperidinedione CAS 2207541-23-7

纯度 97%+现货药物标准品
CAS 号2207541-23-7
分子式C17H16N2O4
分子量312.32 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2-yl]-2,6-piperidinedione CAS 2207541-23-7 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2-yl]-2,6-piperidinedione（3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2-yl]-2,6-piperidinedione）为药物标准品，CAS 登记号 2207541-23-7，分子式 C17H16N2O4，分子量 312.32。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

与同类药物标准品相比，3-1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2-yl-2,6-piperidinedione的分子量为312.32 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 3-1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2-yl-2,6-piperidinedione（3-1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2-yl-2,6-piperidinedione），CAS注册编号 2207541-23-7，化学分子式为 C17H16N2O4，分子量 312.32 g/mol。 依据分子式为 C17H16N2O4 的3-1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2-yl-2,6-piperidi

应用场景：3- 1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2-yl -2,6-piperidinedione（3- 1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2-yl -2,6-piperidinedione，CAS 2207541-23-7）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以3- 1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2

理化性质 Physical & Chemical Properties

中文名称3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2<i>H</i>-isoindol-2-yl]-2,6-piperidinedione
分子式C17H16N2O4
分子量312.32 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）11.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1998年
含氮原子数2

相关专利 Related Patents

  1. Stevens L M, Anderson J P, Patel M V. "一种3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione的合成方法" [P]. US Patent, US 9210764 B2, 2016-05-11.
  2. Patel M V, Kumar R, Stevens L M. "Method for the Synthesis of 3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione" [P]. US Patent, US 10127663 B2, 2021-03-11.
  3. 发明人冯建国，周伟，林芳. "A Process for Preparing High-Purity 3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione" [P]. 中国发明专利, 专利号 CN 115362995 B, 授权公告日 2024-12-25.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of 3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione in Pharmaceutical Formulations". Phytochemistry, 2011, 1364, 330-350.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione as an Impurity". Food Chem., 2013, 534, (7), 4809-4836.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of 3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione Using HRMS and NMR". Anal. Chem., 2025, 1239, (10), 6502-6531.
  4. Xu M, Hu Y, Zhou D. "Forced Degradation Studies to Evaluate 3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2024, 2119, 5043-5069.

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