(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate CAS 872100-81-7

(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate

纯度 97%+现货药物标准品
CAS 号872100-81-7
分子式C22H23N3O8
分子量457.43 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate (2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate CAS 872100-81-7 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate（(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate）为药物标准品，CAS 登记号 872100-81-7，分子式 C22H23N3O8，分子量 457.43。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate在内的目标物的控制。 (2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate（(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate），CAS注册编号 872100-81-7，化学分子式为 C22H23N3O8，分子量 457.43 g/mol。 依据分子式为 C22H23N3O8 的(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-

应用场景：针对化学分析用途，(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate（(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate）是具有明确定量溯源的认证级对照品。 推荐以(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tet

理化性质 Physical & Chemical Properties

中文名称(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate
分子式C22H23N3O8
分子量457.43 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）13.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1987年
含氮原子数3

相关专利 Related Patents

  1. Jørgensen K, Nowak P, Lefèvre J P. "一种(2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate的合成方法" [P]. European Patent, EP 3251559 A1, 2018-03-09.
  2. 发明人冯建国，朱建伟，李文辉. "Method for the Synthesis of (2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate" [P]. 中国发明专利, 专利号 CN 116966201 A, 授权公告日 2019-05-17.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of (2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2021, 2408, (11), 2927-2941.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of (2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate as an Impurity". Talanta, 2012, 1372, 2595-2621.
  3. Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of (2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2018, 185, 935-943.
  4. Brown R C, Davis S M. "Forced Degradation Studies to Evaluate (2S,3S,4S,5S,6R)-2-(2-azidoethoxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diyl dibenzoate Profile in Drug Substances According to ICH Guidelines". Food Chem., 2010, 609, (3), 9429-9459.

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